Manchester United struck twice in the closing 10 minutes at Elland Road, leaving Leeds in severe trouble.
Marcus Rashford broke the deadlock when he rose to meet Luke Shaw’s curling cross and headed past Illan Meslier for his 21st goal of the season.
Substitute Alejandro Garnacho then outpaced the home defense before beating Meslier at his near post, much to the delight of manager Erik ten Hag.
The result was harsh on Leeds, who created a number of decent opportunities but could not beat visiting goalkeeper David de Gea.
That work continues knowing if Everton win Monday’s Merseyside derby at Anfield, Leeds will drop into the bottom three.
